A comprehensive genomic analysis of single cells is needed for numerous scenarios in tumor genetics, clinical diagnostics and forensic application. PCR protocols were developed which allow an unbiased ...
A collaborative study emanating from the Sanger Institute, for example, explored global variation in copy number in the human genome using both array-based CGH and SNP genotyping, describing it as ...
The introduction of array comparative genome hybridization (CGH) into prenatal genetic diagnosis presents both challenges and controversy to the clinical cytogenetic community. The challenges are ...
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