Glutamate receptors, including AMPA and NMDA subtypes, are pivotal mediators of excitatory transmission and plasticity across the mammalian central nervous system. Their regulation, which involves ...

Matrix metalloproteinases (MMPs) are a family of extracellular, zinc-dependent endopeptidases that have emerged as pivotal regulators of neural plasticity and synaptic function. In the brain, MMPs ...

As animals experience new things, the connections between neurons, called synapses, strengthen or weaken in response to events and the activity they cause in the brain. Neuroscientists believe that ...

Shedding light on how the brain fine-tunes its wiring during learning, a new study finds that different dendritic segments of a single neuron follow distinct rules. The findings challenge the idea ...

By adding, removing, strengthening, or weakening synaptic contacts, our brain encodes new events or forgets previous ones. In AD, synaptic plasticity, the brain's ability to regulate the strength of ...

In December of 1993, former World Boxing Champion John Famechon (who had sustained severe incapacitating brain injuries in August 1991) began a new, complex multi-movement therapy and rehabilitation ...

How do we learn something new? How do tasks at a new job, lyrics to the latest hit song, or directions to a friend’s house become encoded in our brains? The broad answer is that our brains undergo ...