Targeted nerve blocks sharply reduce pain, opioid use for children with severe leg fractures, study finds

A new multicenter study led by Zachary Binder, MD, associate professor of pediatrics, provides compelling evidence that an ultrasound-guided nerve block can dramatically improve pain control for ...
ascopubs.org

ADAGIO: A Phase IIb, Open-Label, Single-Arm, Multicenter Study Assessing the Efficacy and Safety of Adavosertib (AZD1775) as Treatment for Recurrent or Persistent Uterine ...

Primary Analysis of EPIK-O/ENGOT-ov61: Alpelisib Plus Olaparib Versus Chemotherapy in Platinum-Resistant or Platinum-Refractory High-Grade Serous Ovarian Cancer Without BRCA Mutation Eligible patients ...
ascopubs.org

A multi-center study on the role of ACSL4 in invasion and metastasis of hepatocellular carcinoma.

Ivonescimab (PD-1/VEGF bispecific antibody) combined with HAIC for first-line treatment of unresectable hepatocellular carcinoma (uHCC): A prospective, single-arm phase II study. TACE with or without ...
Becker's Spine Review

Study supports Genesys Spine SI Joint fusion system

Genesys Spine’s SIros lateral SI joint fusion system was found to be safe and effective following a multicenter clinical study, the company said in a Feb. 6 news release. The study, published in Pain ...
EurekAlert!

Shriners Children’s launching multi-center study to prompt changes in care and insurance coverage for burn patients

Shriners Children’s is leading a multi-center study that they hope will improve standards of care for burn patients everywhere and could potentially lead to insurance companies changing their coverage ...
The Lancet

Machine learning prediction of 1-year mortality in older patients with heart failure: a nationwide, multicenter, prospective cohort study

A machine learning model incorporating functional assessments predicts one-year mortality in older patients with HF and improves risk stratification beyond established scores. Functional status at ...