Mitochondria organelles came from primordial bacterial endosymbionts and still preserve distinct genes for important functions like making ATP. To speed the emerging therapeutic research into the ...

This partial figure from the paper illustrates the steps taken to compare the mitochondria of young and old mice. First, thin tissue slices were imaged with an advanced imaging method called serial ...

We can all recognise that feeling of muscle fatigue after taking a brisk walk, cycling, running or playing football. Our ability to engage in physical activity for long periods of time is thanks to ...

Many of us remember from high school biology class that mitochondria are the cell's "power plants." These small kidney-bean-shaped structures are what convert nutrients from food into ATP—the cell's ...

Beyond their role as the cell’s powerhouses, mitochondria are dynamic signaling hubs that influence immunity, stress responses, and even genetic regulation. The citric acid cycle not only fuels ATP ...

The evidence is amassing that alterations in brain energy metabolism are the first cause of all psychiatric disorders, from anxiety to schizophrenia, autism to Alzheimer’s disease. The metabolic ...