To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

Example of super-resolution microscopy: The image shows how the Discrete Molecular Imaging (DMI) technology visualizes densely packed individual targets that are just 5 nanometer apart from each other ...

What is Single-Molecule Localization Microscopy? Single-molecule localization microscopy (SMLM) is a super-resolution imaging technique that enables the visualization of biological structures and ...

The resolution of the microscope is limited by the physics of light and the system itself, so the instrument can only detect the sum of these individual contributions—their combined brightness. Like ...

Scientists developed a new microscope based on Brillouin scattering -- a phenomenon where light interacts with naturally occurring thermal vibrations within materials, from which their mechanical ...

Researchers have developed a new microscope that can visualize the optical response of surfaces at an unprecedented spatial resolution of one nanometer. This paves the way for optical microscopy of ...

Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

This is an exciting time for polymer electron microscopy. Recent improvements in instrumentation are pushing resolution limits to remarkable new heights, achieving imaging at 0.5 Å, while dual beam ...

An artist's representation of the new Brillouin microscopy approach that allows entire light-sheets to interact with 3D biological samples. The scattered light reveals a unique optical interference ...

Researchers at the European Molecular Biology Laboratory (EMBL) say they have made an important leap forward with a novel methodology that adds an important microscopy capability to life scientists’ ...