A microarray experiment involves several steps, including spotting complementary DNA, extracting RNA, labeling the probe, hybridizing, scanning and analyzing images. Each step introduces variability, ...

Figure 1: cDNA microarray analysis of DNA copy-number changes. Figure 3: Genome-wide mapping of DNA copy-number variation for breast cancer cell line BT474. Figure 4: High-resolution analysis of ...

The main steps involved and limitations of microarray analysis will be encountered. Two stages can be distinguished in microarray experiments: a pre-microarray experiment phase (tissue handling) and ...

Yes, many are attracted to next-generation sequencing, but loyalty to chip-based phenotyping has its rewards, particularly in screens of large sample sets. The microarray, the legacy technology for ...

Surface plasmon resonance imaging (SPRi) brings label-free detection of molecular interactions to microarray analysis. The arrayed molecules (probes) may be proteins, peptides, nucleic acids, sugars, ...

The Nottingham Prognostic Index (NPI) applied to 467 patients (pts) with a long-term follow-up that were treated in a single institution No significant financial relationships to disclose. This is an ...

Reviewed by Dr. Tomislav Meštrović, MD, Ph.D. The microarray is a recently developed technology used in cancer research and in the pharmacological treatment of other diseases such as oral lesions. In ...

In each type of cell, like a muscle cell or a skin cell, different genes are expressed (turned on) or silenced (turned off). If the cells that are turned on mutate, they could—depending on what role ...

No significant financial relationships to disclose. This is an ASCO Meeting Abstract from the 2004 ASCO Annual Meeting. This abstract does not include a full text component.