The latest short science news items from C&EN. Open an introductory chemistry textbook. What is a covalent bond? A covalent bond occurs when atoms share electrons in a molecule. What is a hydrogen ...

Chemical bonding is the force of attraction that holds atoms together to form molecules or compounds. There are two primary types of chemical bonds: ionic and covalent bonds. Both these bonds play a ...

One class of drugs that has shown promise in treating diseases ranging from lung cancer to COVID-19 are targeted covalent inhibitors (TCIs). These small molecule drugs form covalent bonds with their ...

Chemical probes that form a covalent bond with a protein target often show enhanced selectivity, potency and utility for biological studies. Despite these advantages, protein-reactive compounds are ...

Graphene oxide is composed of oxygenated functional groups, the most prevalent of which are carboxyl, carbonyl, epoxy, and hydroxyl. These functional groups present on graphe are polar, making it very ...

When most small-molecule drugs meet a protein target, they nestle close to their intended. But the flirtatious relationship between drug and target is often fleeting, with the drug repeatedly drifting ...