EurekAlert!

Effectiveness of machine learning at modeling the relationship between Hi-C data and copy number variation

Copy number variation (CNV) refers to an increase or decrease in the number of copies of a DNA sequence in a genome, which can subsequently be implicit in promoting aberrant gene expression patterns ...
Business Wire

New Data from Universal DX: Combining Copy Number Variation (CNV) with cfDNA Fragment Size Information Could Serve as Promising New Avenue for Early Detection of Colorectal ...

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Universal Diagnostics (Universal DX), a bioinformatics and multi-omics company on a mission to transform cancer into a curable disease, today announced the results ...
ascopubs.org

Assessing the Detection Power of Genome-Wide Copy Number Variation Profiles in Prostate Cancer Using Simulated Shallow Whole-Genome Sequencing Data

Causal Cascade of Symptoms on Patient Functioning and Health-Related Quality of Life in Non–Small Cell Lung Cancer and Metastatic Breast Cancer Shallow whole-genome sequencing (sWGS) is a ...
Nature

Amylase Gene Copy Number Variation and Its Impact on Obesity and Diabetes

The amylase gene family, particularly AMY1, exhibits extensive copy number variation (CNV) that modulates salivary amylase production and, consequently, the efficiency of dietary starch digestion.
EurekAlert!

Size matters: genome size dynamics driven by copy number variation in a green alga

SMBE Journals (Molecular Biology and Evolution and Genome Biology and Evolution) Generating genome sequence data from six additional C. psl. strains that differed markedly in the size of their genomes ...
Business Wire

Mission Bio Launches Innovative Single-cell Genome Integrity Solution to Measure Whole Genome Copy Number Variation in Advanced Therapies and Tumor Samples

SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Mission Bio, a leader in single-cell multiomics solutions for precision medicine, today announced the launch of its Tapestri® Genome Integrity CNV ...
Labroots

CYP2D6 Copy Number Determination using Digital PCR

Accurate prediction of CYP2D6 activity from genotype data is of utmost importance as CYP2D6 pharmacogenetic (PGx) testing is increasingly used to guide drug therapy. However, given the complexity of ...