Innate immunity constitutes the body’s first line of defence against invading pathogens. This ancient, evolutionarily conserved system is activated within minutes of encountering foreign agents, ...

Innate lymphoid cells, which curiously behave like T cells even though they don’t recognize specific antigens, show promise as a potential cancer therapeutic. In the years that followed, other groups ...

Cancer immunotherapies, including cancer vaccines, harness and amplify the immune system’s natural ability to detect and attack cancer cells. In this illustration, immune T cells (pink) attach to a ...

Researchers have discovered that mRNA-based COVID-19 vaccines have a persistent effect on the innate immune system. These mechanisms may help the human body to better protect itself against potential ...

Most people infected with the SARS-CoV-2 virus recover after the acute illness. However, a significant proportion of infected individuals develop long-lasting symptoms with a wide range of ...

During the recent Covid-19 pandemic, the rate of serious illness and death was jarringly high in older populations. Why? Weakening immune systems — as we age, we become more vulnerable to infections, ...

Researchers have shown that innate immune training, also known as trained immunity (TRIM), leads to aggravated bone loss in experimental models of periodontitis and inflammatory arthritis. Clinical ...

Dianthus achieved its NASDAQ listing last year via a merger with Magenta Therapeutics. The company is focused on development of a single drug candidate, DNTH-103, which targets the complement system, ...

Antibodies, which recognize viruses and proteins that the body has encountered before, have long gotten most of the credit for giving the human immune system a memory. Now, researchers at the ...

Antimicrobial resistance (AMR) poses one of the greatest threats to global public health, with excessive antibiotic use driving the emergence of ...

Tom Anchordoquy receives funding for this work from the Nationals Institutes of Health through grant # RO1 CA289447. When the first cells appeared on Earth approximately 3.8 billion years ago, viruses ...