A research team led by investigators at McMaster University has identified an axonal guidance signaling pathway that cancer cells use to infiltrate the brain. The combined results of preclinical in ...

Neurotrophins are essential proteins that support the growth, survival, and differentiation of neurons. Among these, brain-derived neurotrophic factor (BDNF) plays a crucial role in neuronal signaling ...

A cross-sectional image of the mouse cerebral cortex in enlargement. The same method was applied as in the ferret. The cerebral cortex is shown in blue and some neurons are dyed green with GFP. In ...

A new pathway that is used by cancer cells to infiltrate the brain has been discovered by a team of Canadian and American research groups led by the Singh Lab at McMaster University. The research also ...

A new study definitively reveals the existence of a system that had been theorized to clear metabolic wastes in the human brain. The study uses imaging in neurosurgery patients to show how brain's ...

Discover how white matter changes in the brain can predict aging trajectories and cognitive decline in individuals.